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 Allopurinol tablets 300mg №30

Allopurinol tablets 300mg №30


(In stock)

  •  Allopurinol tablets 300mg №30  Allopurinol tablets 300mg №30

Allopurinol tablets 300mg №30

Diseases associated with hyperuricemia (treatment and prevention): gout (primary and secondary), urolithiasis (with urate formation).

Hyperuricemia (primary and secondary) occurring in diseases accompanied by increased breakdown of nucleoproteins and elevated uric acid levels in the blood, including various hematological malignancies (acute leukemia, chronic myeloid leukemia, lymphosarcoma, etc.), during cytostatic and radiation therapy for tumors (including in children), psoriasis, extensive traumatic injuries, due to enzymatic disorders (Lesch-Nyhan syndrome), as well as during massive glucocorticoid therapy, where the intensive tissue breakdown significantly increases the amount of purines in the blood.

Uric acid nephropathy with impaired kidney function (renal insufficiency).

Recurrent mixed oxalate-calcium kidney stones (with uricosuria).

Availability: In stock

on orders over $70
Our Location
New York, USA
Processing Time
1-2 Business Days

This information is for general purposes only and should not be considered as medical advice. Always consult with a qualified healthcare professional for any medical concerns or questions you may have.

<p>Allopurinol is a structural analogue of hypoxanthine. Allopurinol, as well as its primary active metabolite - oxypurinol, inhibits xanthine oxidase - an enzyme that converts hypoxanthine to xanthine and xanthine to uric acid. Allopurinol reduces the concentration of uric acid in the serum and urine, thereby preventing the deposition of uric acid crystals in tissues and/or promoting their dissolution. Besides suppressing purine catabolism in some (but not all) patients with hyperuricemia, a large amount of xanthine and hypoxanthine becomes available for the reformation of purine bases, leading to the inhibition of de novo purine biosynthesis through a feedback mechanism mediated by the suppression of the enzyme hypoxanthine-guanine phosphoribosyltransferase. Other metabolites of allopurinol include allopurinol riboside and oxypurinol-7 riboside.<\p>

Additional Information
SKU 23133
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