Diseases associated with hyperuricemia (treatment and prevention): gout (primary and secondary), urolithiasis (with urate formation).
Hyperuricemia (primary and secondary) occurring in diseases accompanied by increased breakdown of nucleoproteins and elevated uric acid levels in the blood, including various hematological malignancies (acute leukemia, chronic myeloid leukemia, lymphosarcoma, etc.), during cytostatic and radiation therapy for tumors (including in children), psoriasis, extensive traumatic injuries, due to enzymatic disorders (Lesch-Nyhan syndrome), as well as during massive glucocorticoid therapy, where the intensive tissue breakdown significantly increases the amount of purines in the blood.
Uric acid nephropathy with impaired kidney function (renal insufficiency).
Recurrent mixed oxalate-calcium kidney stones (with uricosuria).
Chronic intoxication in infections and gastrointestinal diseases (dysentery, salmonellosis, typhoid fever, cholera, hepatitis, cirrhosis of the liver, intestinal dysbiosis, functional gastrointestinal dyspepsia, pancreatitis, enterocolitis, peptic ulcer disease, nonspecific ulcerative colitis); allergies — toxicodermia, allergic dermatoses, pollinosis, angioedema, neurodermatitis, allergic bronchitis, bronchial asthma; alcoholism (including hangover syndrome), acute poisonings, pyelonephritis, renal insufficiency; purulent and burn wounds, postoperative inflammatory complications; metabolic disorders; atherosclerosis and obesity (prevention and treatment).